Main Characters
| Ash | Misty | Brock |
| Pikachu | Jesse | James |
| Meowth | May | Max |
Supporting Characters
| Professor Oak | Delia Ketchum | Nurse Joy |
| Officer Jenny | Tracey Sketchit |
Reoccurring roles
| Gary Oak | Richie | Todd (Snap?) |
| Giovanni | Butch | Cassidy |
| Wobuffet | Mr Mime (Mimie) | Team Rocket |
| Team Aqua | Team Magma | Misc. professors |